Before sharing sensitive information, make sure youre on a federal government site. The condensation of acetone (hence the suffix 'A' in the name)[32] with two equivalents of phenol is catalyzed by a strong acid, such as concentrated hydrochloric acid, sulfuric acid, or a solid acid resin such as the sulfonic acid form of polystyrene sulfonate. BPA is regularly used to strengthen products for human health and safety. The epoxide resins (also widely known as epoxy resins and, occasionally, as ethoxyline resins) are characterised by the possession of more than one 1,2-epoxy group (I) per molecule. BPA is an industrial chemical used to make a hard, clear plastic known as polycarbonate. [103], BPA is an environmental contaminant of emerging concern. . Is there concern that exposure to BPA can cause harm or result in serious diseases? . When possible, opt for glass, porcelain or stainless steel containers, particularly for hot food or liquids. This results in much lower internal exposure of BPA (i.e., the active form) than what occurs from other routes of exposure such as injection. The hydroxy group may be derived from aliphatic diols, polyols (polyether polyols), phenolic compounds or dicarboxylic acids. Bisphenol-A, commonly abbreviated as BPA, is an organic compound with the chemical formula (CH 3) 2 C (C 6 H 4 OH) 2 belonging to the group of diphenylmethane derivatives and bisphenols, with two hydroxyphenyl groups. It is found in various products including shatterproof windows, eyewear, water bottles, and epoxy resins that coat some metal food cans, bottle tops, and water supply pipes. Many BPA-containing materials are non-obvious but commonly encountered,[17] and include coatings for the inside of food cans,[18] clothing designs,[19] shop receipts,[20] and dental fillings. [17] Although BPA exposure is common it does not accumulate within the body, with toxicokinetic studies showing the biological half-life of BPA in adult humans to be around two hours. fatty acid dimers, +undefined-86-13650506873 +undefined-86-13650506873. If youve ever read a news article or blog post about chemicals, you may have heard the oft-cited claim that there are 84,000 chemicals in commerce but only 200 of these have been tested for safety. The ACC petition demonstrated, from publicly available information and information collected from industry sources, that the use of polycarbonate resins in baby bottles and sippy cups had been abandoned. Physical State: Powder. 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[73] Concern is mostly related to its estrogen-like activity, although it can interact with other receptor systems as an endocrine-disrupting chemical. Commercial production of BPA requires distillation either extraction of BPA from many resinous byproducts under high vacuum or solvent-based extraction using additional phenol followed by distillation. Polycarbonate plastic provides the benefit of long-lasting transparency and durability in new, design-inspired LED lighting in vehicles. Strong, shatter-resistant polycarbonate is used for helmets and protective sports visors to help protectchildren and athletes from injuries. Toxicity evaluation of bisphenol a administered by gavage to sprague dawley rats from gestation day 6 through postnatal day 90. Phenol is a man-made chemical, although it is also found naturally in animal waste and decomposing organic material. [90] It can also protect it from deactivation from the SERM 4-hydroxytamoxifen (afimoxifene). BPA can also be found in breast milk. Bisphenol Resin. You can also browse global suppliers,vendor,prices,Price,manufacturers of Bisphenol A epoxy resin(). Among the various polymers available as resins for composites [26][27][28][29][30][31], epoxy resins are chosen because of their excellent adhesion to many substrates and their high thermal and . Toxicol Appl Pharmacol. Bisphenol A is a chemical compound containing two phenol functional groups. 2011 Dec 15;207(3):298-305. f) Doerge DR, Twaddle NC, Vanlandingham M, Fisher JW. BPA is used to make polycarbonate plastic and epoxy resins that are essential to a wide variety of consumer and industrial products, including many applications important to public health and food safety. 12 oz. While there have been many hundreds of studies on BPA, none has shown a direct cause-and-effect relationship between BPA and any human health effects. Brand Names: Not applicable . Global production in 2022 is expected to reach 10 million tonnes. BPA is best known for its use in the manufacture of polycarbonate plastics and epoxy resins, particularly those found in water bottles, baby bottles, and other beverage and food containers. BPA is a starting material for the synthesis of plastics, primarily certain polycarbonates and epoxy resins, as well as some polysulfones and . [48] BPA is a major component of several high-performance plastics, the production of these is low compared to other plastics but still equals several thousand tons a year. In addition, FDA actively supported and participated in the Expert Consultation on BPA convened by World Health Organization and the Food and Agriculture Organization of the United Nations on November 2-5, 2010, in Ottawa, Canada. Chemical Identity. (sometimes called a dimer) is called bisphenol F, which is an important monomer in the production of epoxy resins. resins are bisphenol A diglycidyl ether (DGEBA) and epoxy phenol Its optical clarity allows direct observation of blood or other fluids to monitor proper flow. Epoxy resins are typically formed by the reaction of compounds containing at least two active hydrogen atoms (polyphenolic compounds, diamines, amino phenols, heterocyclic imides and amides, aliphatic diols, etc.) 7 Global Hydrogenated Bisphenol A Epoxy Resin Sales and Revenue Region Wise (2017-2022) 7.1 Global Sales and Market Share, Region Wise (2017-2022) 7.2 Global Revenue (Revenue) and Market Share . Polycarbonate plastic is a lightweight, high-performance plastic that possesses a unique balance of toughness, optical clarity, high heat resistance, and excellent electrical resistance. 08-5994, September 2008. Thanks to their high strength, versatility, and excellent adhesion to a variety of surfaces, epoxy resins have gained wide acceptance in diverse applications (coatings, electrical, casting resins, composites, etc.). Bisphenol A- (epichlorhydrin)epoxy resin, polymer with polyethylene glycol, castor oil and triethylenetetramine IUPAC names 1 Print infocard Substance identity Substance identity The 'Substance identity' section is calculated from substance identification information from all ECHA databases. [90] Different expression of ERR- in different parts of the body may account for variations in bisphenolA effects. Dont microwave polycarbonate plastic food containers. BPA is an industrial chemical used to make polycarbonate, a hard, clear plastic, which is used in many consumer products. .mw-parser-output .ib-chembox{border-collapse:collapse;text-align:left}.mw-parser-output .ib-chembox td,.mw-parser-output .ib-chembox th{border:1px solid #a2a9b1;width:40%}.mw-parser-output .ib-chembox td+td{width:60%}, Bisphenol A (BPA) is a chemical compound primarily used in the manufacturing of various plastics. [12][13][14] BPA is a xenoestrogen, exhibiting hormone-like properties that mimic the effects of estrogen in the body. (the chemical formula is shown in Fig. [2][7] BPA is produced on an industrial scale by the condensation of phenol and acetone, and has a global production scale which is expected to reach 10 million tonnes in 2022.[8]. Epoxy resins have many uses including engineering applications such as electrical laminates for printed circuit boards, composites, paints and adhesives, as well as in a variety of protective coatings. Properties of copolymer epoxy resins. [4] The studies were evaluated for their relevance for regulatory hazard and/or risk assessment. FDAs current perspective, based on its most recent safety assessment, is that BPA is safe at the current levels occurring in foods. :30583-72-3 Molecular formula:C18H33ClO3 Molecular weight: 332.91 Appearance:Colorless liquid Assay 60% Hydrogenated Bisphenol A Epoxy Resin Specification: Hydrogenated Bisphenol A Epoxy Resin Application Find out about the exciting discoveries being made by NIEHS and NIEHS-supported researchers that are helping to improve health and save lives. Since that time, the FDA has continued to review additional studies as they became available, including those addressing possible low-dose effects. Bisphenol A diglycidyl ether (DGEBA) can be called a small-molecule adhesive. 133 Cecil Street, Pharmacokinetics of bisphenol A in serum and adipose tissue following intravenous administration to adult female CD-1 mice. The chemical formula of Bisphenol A is C15H16O2. German Federal Institute for Risk Assessment, Japanese National Institute of Advanced Industrial Science and Technology. 2011 Nov 15;257(1):122-36. i) Doerge DR, Vanlandingham M, Twaddle NC, Delclos KB. It is found in various products including shatterproof windows, eyewear, water bottles, and epoxy resins that coat some metal food cans, bottle tops, and water supply pipes. Polycarbonate plastic also is used to make housings for electronic products such as cell phones and laptops, as well as optical discs such as CDs and DVDs. Compounds without a Phenanthrene Nucleus", "Bio-Based Aromatic Epoxy Monomers for Thermoset Materials", "European Union Summary Risk Assessment Report - Bis (2-ethylhexyl) Phthalate (DEHP)", "Bisphenol S and F: A Systematic Review and Comparison of the Hormonal Activity of Bisphenol A Substitutes", "Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004", "The state of bisphenol research in the lesser developed countries of the EU: a mini-review", "An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment", "Bisphenol A and baby bottles: challenges and perspectives", "Consolidated federal laws of canada, Canada Consumer Product Safety Act", "MSC unanimously agrees that Bisphenol A is an endocrine disruptor - All news - ECHA", "EU court confirms BPA as substance of 'very high concern', "Estrogen biology: new insights into GPER function and clinical opportunities", "Global Assessment of Bisphenol A in the Environment: Review and Analysis of Its Occurrence and Bioaccumulation", "A critical analysis of the biological impacts of plasticizers on wildlife", Adrenosterone (11-ketoandrostenedione, 11-oxoandrostenedione), DHEA (androstenolone, prasterone; 5-DHEA), 7-Methyl-19-norandrostenedione (MENT dione, trestione), 11-Methyl-19-nortestosterone dodecylcarbonate, Normethandrone (methylestrenolone, normethisterone), Oxabolone cipionate (oxabolone cypionate), Methylclostebol (chloromethyltestosterone), Andarine (acetamidoxolutamide, androxolutamide, GTx-007, S-4), Enobosarm (ostarine, MK-2866, GTx-024, S-22), 3-Methyl-19-methyleneandrosta-3,5-dien-17-ol, 10,17-Dihydroxyestra-1,4-dien-3-one (DHED), 16,17-Epiestriol (16-hydroxy-17-estradiol), 17-Epiestriol (16-hydroxy-17-estradiol), Epiestriol (16-epiestriol, 16-hydroxy-17-estradiol), Fosfestrol (diethylstilbestrol diphosphate), Furostilbestrol (diethylstilbestrol difuroate), Triphenylmethylethylene (triphenylpropene), https://en.wikipedia.org/w/index.php?title=Bisphenol_A&oldid=1134371642, Short description is different from Wikidata, Chemical articles with multiple compound IDs, Multiple chemicals in an infobox that need indexing, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License 3.0, Polycyanurates can be produced from BPA by way of its di-, Bisphenol-A formaldehyde resins are a subset of, BPA is used as an antioxidant in several fields, particularly in, Several drug candidates have also been developed from bisphenol A, including, Reprinted in condensed form in: A. Dianin (1892), This page was last edited on 18 January 2023, at 10:18.

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